The GLP-1 telehealth market looks completely different now than it did eighteen months ago. A Novo Nordisk settlement in March 2026 forced dozens of platforms to drop or rethink compounded semaglutide. The FDA sent warning letters to more than thirty compounding operations in early 2026. Lilly started selling oral orforglipron direct to patients around April 2026 at roughly $149 a month. People asking around in forums and Reddit threads keep hitting the same questions: who actually ships fast, who is transparent about their pharmacy, and who won’t surprise you with fees after you sign up. I went through the pricing pages, pharmacy disclosures, and recurring complaints for all ten. Here’s what I found.
1. HealthRX
The single thing that keeps coming up in recommendations for HealthRX is the combination of low entry pricing and named-pharmacy transparency. Compounded semaglutide starts at $99 a month. Compounded tirzepatide starts at $149. Those are cash prices, no insurance gymnastics required.
What earns the top slot here is not just price. HealthRX dispenses through Manifest Pharmacy in Greer, South Carolina, a 503A compounding pharmacy operating under USP-797 standards with lot-level tracking from production to delivery. LegitScript certified it under certificate number 50087439. A lot of telehealth brands mention “a licensed compounding pharmacy” and stop there. Manifest is named, located, and verifiable.
A board-certified physician reviews your intake within about 24 hours. Orders go out overnight at no shipping cost, anywhere in the country. The clinical data it points to comes from actual trials, not internal claims: roughly 21% average body weight reduction at 72 weeks for tirzepatide (SURMOUNT-1) and about 15% at 68 weeks for semaglutide (STEP 1). These are compounded medications, not FDA-approved branded products. That distinction matters.
For cash-pay patients who want speed, price, and a pharmacy they can actually look up, HealthRX is the strongest current option in this category.
2. FormBlends
FormBlends runs a similar compounded GLP-1 telehealth model with physician oversight and a 503A-registered pharmacy, but it appeals to a different kind of buyer. Pricing is higher: semaglutide runs around $299 per vial, tirzepatide around $349. What you get for that premium is published purity documentation. HPLC purity percentages, mass spectrometry identity confirmation, endotoxin and sterility results, all listed per product. Most GLP-1 telehealth brands do not publish this level of batch testing at all.
Ships to 47 states. The other notable difference is that FormBlends carries a wide peptide catalog beyond GLP-1s, things like recovery and cognitive peptides, under the same clinician model. If you want one provider for GLP-1 therapy plus other peptide protocols, this is one of the few telehealth operations structured for that. It ranks below HealthRX on price and geographic reach, but for the patient who specifically wants documentation on what’s in the vial, it earns its place.
3. Mochi Health
Mochi uses board-certified obesity-medicine clinicians, not general practitioners. That’s a meaningful difference in this category. Monthly costs land at roughly $99 for compounded semaglutide and $199 for compounded tirzepatide. The monitoring is more structured than some cheaper options, which makes it a reasonable choice for patients who want more clinical hand-holding.
4. Hims & Hers
After the March 2026 settlement, Hims & Hers moved away from compounded GLP-1s toward branded options. Injectable Wegovy is listed around $299 a month, oral semaglutide around $249, and Zepbound around $399. With insurance plus a savings card, costs can drop to nearly nothing. Big brand, broad reach, but you’re now in the branded-med pricing structure.
5. Ro Body
Ro’s first month runs about $39, then $74 to $149 for the membership, with medications billed separately. They have a prior-authorization team specifically to help patients get branded meds covered by insurance. Worth a look if your insurance situation is complicated.
6. Found
Found charges roughly $99 a month for the platform, medications extra. It bundles coaching into the base fee, which appeals to people who want behavioral support woven into the clinical side rather than bolted on as an upsell.
7. PlushCare
PlushCare’s membership is $19.99 a month, which is the lowest platform fee on this list. It focuses on branded medications and takes insurance. Same-day visits are often available. The model is leaner on the weight-management-specific support side, but the access and pricing make it worth knowing about.
8. Henry Meds
Cash-pay compounded GLP-1s, $179 to $249 for the first month, with shipping in 24 to 72 hours. Henry keeps the clinical overhead lighter, which is part of how it keeps costs down. Faster to get started than more monitoring-heavy platforms.
9. Form Health
Form Health pairs an MD with a registered dietitian on every case. About $299 a month plus labs and medications. The most premium model on this list, and priced that way. Not built for people who want to minimize spend. Built for people who want close, professional supervision over a long program.
10. Sesame
Sesame works differently from all of the above. It’s a marketplace where you pay an annual fee (from about $59 a month) and then book individual visits. Medications are separate and priced per prescription. Flexible, but requires more self-direction than a managed program.
Common Questions
If a virtual weight loss clinic uses a compounded GLP-1, how do I know the medication is actually what they say it is?
Ask for batch-level third-party testing documentation before you order. FormBlends publishes HPLC purity percentages, mass spectrometry identity results, and sterility data per product. Most platforms do not go that far. At minimum, confirm the dispensing pharmacy is a named 503A facility you can independently verify through your state board of pharmacy.
Does it matter whether the prescribing clinician specializes in obesity medicine, versus a general practitioner?
Yes, practically speaking. Mochi Health specifically uses board-certified obesity-medicine physicians, which means they’re trained to manage GLP-1 dosing, plateaus, and side effects as a specialty, not as a side service. General practitioners can legally prescribe these medications, but their familiarity with titration protocols and long-term management varies considerably.
After the March 2026 Novo Nordisk settlement, which of these platforms still offer compounded semaglutide?
HealthRX and Henry Meds continued offering compounded GLP-1s after the settlement. Hims & Hers shifted its model toward branded options like Wegovy and Zepbound. Platform offerings in this space change quickly, so verify current availability directly with any clinic before signing up.
What’s the actual cost difference between a low-overhead platform like PlushCare and a full-supervision program like Form Health?
PlushCare’s platform fee is $19.99 a month, with branded medications billed separately through insurance. Form Health runs about $299 a month before labs and medications. The gap is real, but so is what you get: Form Health assigns both an MD and a registered dietitian to every patient, which is a structurally different level of involvement.
Is Sesame a viable option if I want GLP-1 medication without committing to a monthly subscription program?
Sesame works for self-directed patients who are comfortable managing their own follow-up. You pay an annual membership fee starting around $59 a month, then book visits and fill prescriptions individually. There’s no managed program or built-in coaching. That flexibility suits some people, but it puts more coordination responsibility on you than any other platform on this list.
A Quick Note
This article reflects publicly available pricing and program structures as of mid-2026. Costs and availability change. Compounded medications are not FDA-approved finished drug products. Consult a physician before starting any GLP-1 therapy.
Sources
- SURMOUNT-1 trial results (tirzepatide), published in *The New England Journal of Medicine*, 2022
- STEP 1 trial results (semaglutide), published in *The New England Journal of Medicine*, 2021
- FDA warning letters to compounding facilities, early 2026, FDA.gov
- Novo Nordisk settlement announcement, March 9, 2026, public press coverage
- LegitScript certification database (public search), LegitScript.com
- Individual brand pricing pages (Hims & Hers, Ro, Mochi Health, Found, PlushCare, Henry Meds, Form Health, Sesame), verified via public-facing websites
